Professor YIN Huiyong’s team has made a significant breakthrough in understanding a mechanism linking hyperuricemia to hypertriglyceridemia
Hyperuricemia (HUA) is diagnosed when the levels of urate in the blood exceed 420 µM, the saturated concentration of urate. In mainland China, the prevalence of hyperuricemia exceeds 17.7% in the adult population, affecting over 185 million individuals. HUA has become the fourth most common chronic metabolic condition in China, following hyperlipidemia, hyperglycemia, and hypertension. Hyperuricemia not only triggers gout but also increases the risk of various metabolic diseases, including obesity, diabetes, cardiovascular and cerebrovascular diseases, hypertension, and kidney disease. Among the 25 million gout patients in China, more than half exhibit abnormal blood lipid levels. Although preliminary analysis suggests that hypertriglyceridemia may be a causal factor for HUA, the underlying mechanism has remained elusive.
4 June 2024
