What’s On
(THU)
9:00 AM – 6:00 PM
Atrium, Ground Floor and Wei Hing Lecture Theatre (LT-2510),Li Dak Sum Yip Yio Chin Academic Building, City University of Hong Kong
(FRI)
生物暗物質：長非編碼 RNA 在平滑肌的功能
JCC Commencement 2024 – Celebrating Excellence in Academics and Research
19 June 2024
On 12 June 2024, the JCC Commencement ceremony proudly recognised the remarkable achievements of our graduating class. It was a day of great pride as we honored the hard work and dedication of our graduating students. But the celebrations did not stop there. We were also delighted to present the prestigious Outstanding Research Award to Prof. Xin Deng, in recognition of his groundbreaking contributions to the field.
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CityUHK and Sun Yat-sen University sign cooperation agreements to establish partnerships in digital medicine and law
24 May 2024
CityUHK and Sun Yat-sen University signed two cooperation agreements to establish partnerships in areas such as digital medicine and law to foster talent nurturing and exchange...
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Professor YIN Huiyong’s team has made a significant breakthrough in understanding a mechanism linking hyperuricemia to hypertriglyceridemia
4 June 2024
Hyperuricemia (HUA) is diagnosed when the levels of urate in the blood exceed 420 µM, the saturated concentration of urate. In mainland China, the prevalence of hyperuricemia exceeds 17.7% in the adult population, affecting over 185 million individuals. HUA has become the fourth most common chronic metabolic condition in China, following hyperlipidemia, hyperglycemia, and hypertension. Hyperuricemia not only triggers gout but also increases the risk of various metabolic diseases, including obesity, diabetes, cardiovascular and cerebrovascular diseases, hypertension, and kidney disease. Among the 25 million gout patients in China, more than half exhibit abnormal blood lipid levels. Although preliminary analysis suggests that hypertriglyceridemia may be a causal factor for HUA, the underlying mechanism has remained elusive.
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Professor Michael YANG’s research excels with funding from the RAISe+ Scheme
29 May 2024
A research project of Prof. Michael Yang, among with other four projects, was granted funds from the HKSAR Government’s Research, Academic, and Industry Sectors One-plus Scheme (RAISe+ Scheme). This demonstrates our commitment to promoting excellence in high-quality research and innovation, driving the transformation of the University’s world-class scientific research into applications, thereby creating commercial and social value.
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Professor Huang Yu wins Peter Harris Distinguished Scientist Award
20 May 2024
We are delighted to announce that Professor Yu Huang has been honoured with the Peter Harris Distinguished Scientist Award by the International Heart Research Society (ISHR). Professor Huang is the first Chinese recipient of this esteemed award, which recognises his lifetime achievements and contributions to major discoveries in cardiovascular science.
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Facilitating skin wound healing and health monitoring via advanced epidermal bioelectronics
4 May 2024
A multidisciplinary research team consisting of members from Prof. Xi Yao and Prof. Mingliang He’s groups has prepared a stable LM electrode with extremely high adhesion strength (8.9 MPa), which can be further adjusted in a wide range. The adjustable adhesion strength can greatly expand the material’s application scenarios.
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PhD Student ZHU Jingyi Receives WESTPAC Best Young Scientist Oral Presentation 2024 Award
3 May 2024
Miss ZHU Jingyi, a PhD student of Prof. Leo Chan, Visiting Associate Professor of BMS, recently received the prestigious WESTPAC Best Young Scientist Oral Presentation 2024 award at the2nd UN Ocean Decade Regional Conference and 11th WESTPAC International Marine Science Conference.
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New Technology Shows Promise in Monitoring Hepatocellular Carcinoma: Circulating Genome-wide Copy Number Analysis
24 April 2024
Cancer is a complex disease characterized by genetic mutations that accumulate over time. Detecting cancer at an early stage is crucial for effective treatment. Scientists have made significant progress in using a non-invasive method called circulating tumor DNA (ctDNA) to detect liver cancer. Circulating cell-free DNA-inferred tumor content has been demonstrated detectable previously in blood samples collected at diagnosis of early-stage cancer. However, limited data has been shown in samples collected prior to cancer diagnosis – “pre-sample”.
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Faculty and Student Gathering Promotes Positive Interaction
19 April 2024
A vibrant and interactive faculty and student gathering took place on 18 April 2024, marking the conclusion of the teaching week. The event, attended by a total of 37 enthusiastic faculty members and students, provided a platform for open dialogue.
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Programmes
Recent
Research
Papers
Fatty acid oxidation-induced HIF-1α activation facilitates hepatic urate synthesis through upregulating NT5C2 and XDH
Liang, N., Yuan, X., Zhang, L., Shen, X., Zhong, S., Li, L., Li, R., Xu, X., Chen, X., Yin, C., Guo, S., Ge, J., Zhu, M., Tao, Y., Chen, S., Qian, Y., Dalbeth, N., Merriman, T. R., Terkeltaub, R., Li, C.*, Xia, Q.* & Yin, H.* (2024). Fatty acid oxidation-induced HIF-1α activation facilitates hepatic urate synthesis through upregulating NT5C2 and XDH. Life Metabolism, loae018.
Liquid Metal-Enhanced Highly Adhesive Electrodes for Multifunctional Epidermal Bioelectronics
Cao, C., Hou, C., Wang, X., Lv, D., Ai, L., Feng, Y., Chen, P., Wang, X., He, M.* & Yao, X.* (2024). Liquid Metal-Enhanced Highly Adhesive Electrodes for Multifunctional Epidermal Bioelectronics. Advanced Functional Materials, 24036712403671.
Monitoring hepatocellular carcinoma using tumor content in circulating cell-free DNA
Lian, S., Lu, C., Li, F., Yu, X., Ai, L., Wu, B. H., Gong, X., Zhou, W., Liang, X., Zhan, J., Yuan, Y., Fang, F., Liu, Z., Ji, M., Zheng, Z.* (2024). Monitoring hepatocellular carcinoma using tumor content in circulating cell-free DNA. Clinical Cancer Research, Epub ahead of print.
Entorhinohippocampal cholecystokinin modulates spatial learning by facilitating neuroplasticity of hippocampal CA3-CA1 synapses
Su, J., Huang, F.*., Tian, Y., Tian, R., Qianqian, G., Bello, S. T., Zeng, D., Jendrichovsky, P., Lau, C. G., Xiong, W., Yu, D., Tortorella, M., Chen, X.* & He, J.* (2023). Entorhinohippocampal cholecystokinin modulates spatial learning by facilitating neuroplasticity of hippocampal CA3-CA1 synapses. Cell Reports, 42:113467.
Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity
Li, H., Wang, X., Wang, Y., Li, Y., Chen, Y., Wong, Y.-T., He, J., & He, M.-L.* (2023). Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity. Signal Transduction and Targeted Therapy, 8(1), 374.
c-di-GMP signaling in Pseudomonas syringae complex
Wang, T., Hua, C., & Deng, X.* (2023). c-di-GMP signaling in Pseudomonas syringae complex. Microbiological Research, 275, 127445.
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BMS Research
Thoughts
Breakthrough in understanding a mechanism linking hyperuricemia to hypertriglyceridemia
Fatty acid oxidation induces hepatic urate synthesis and HUA.
New Technology Shows Promise in Monitoring Hepatocellular Carcinoma
Circulating Genome-wide Copy Number Analysis
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Department of
Biomedical Sciences
City University of
Hong Kong
1A-101, 1/F, Block 1,
To Yuen Building,
31 To Yuen Street,
Kowloon Tong,
Hong Kong
24 June 2024