External Grants

2023

Molecular Mechanism of RNA Transport and Specificity of their Spatial Distribution in Neuron

CRF
2022

Cortical Stimulation to Suppress Tinnitus and Enable Auditory Perception

GRF
2022

Decoding the Worm Brain - Comprehensive Biophysical Mapping and Modeling of the C. Elegans Nervous System

ECS
2022

Elucidating the Dendritic Transport of C1qtnf4 mRNA and the Function of Its Encoded Protein CTRP4 in Dendritic Arborization and Synapse Formation of Neuron

GRF
2022

Elucidating the Role of Phosphorylated Sox9 in Regulating Glycolytic Activities in Neuropathic Pain Pathogenesis

GRF
2022

Factors Determining Sensitivity to Binaural Cues over Binaural Cochlear Implants Investigated Through Behavioral Studies on Rats

Contract Research
2022

Functional Analysis of Transposon Activation in Alzheimer's Disease

ECS
2022

Heterosynaptic Neuroplasticity of the Ascending Inputs in the Auditory Thalamus by Corticothalamic Modulation

GRF
2022

Synthesized CCK-B Receptor Agonists to Alleviate Anterograde Amnesia in Animal Models

CRF
2021

Astrocyte Adrenergic Signaling in the Anterior Cingulate Cortex Contributes to Visceral Pain-Evoked Aversion in Rats

GRF
2021

CCK-B Receptor Antagonist for the Treatment of Depression in the Mouse Model

HMRF
2021

Cellular Mechanisms of Synaptic Functions and Plasticity in Health and Neurodegenerative Diseases

AoE
2021

Cholecystokinin Receptor Agonists as Potential New Drugs for Rescuing Learning and Memory Deficiency in Aged Wild Type and Alzheimer’s Disease Animals

HMRF
2021

Dissecting the Mechanistic Role of A Bioactive Small Molecule in Axon Regeneration as A Potential Therapeutic Target for Nervous System Injuries

GRF
2021

Gene Therapy for Epilepsy through Enhancing Inhibition with High-Frequency Activation of GABAergic Neurons in Mice

GRF
2021

Minimally Invasive in Vivo Detection and Tracking of Neuroinflammation via Glia-Derived Exosomes

GRF
2021

Platform Development for New Anti-epileptic Drug Evaluation and Pre-clinical Study of New Cholecystokinin Antagonists as New Anti-epileptic Drugs

ITF
2021

Targeting P21-Activated Kinases 1 (PAK1) in Neuropathic Pain: Mechanistic Insights and Therapeutic Implications

HMRF
2021

Therapeutic Potential Of Clinically Relevant Small Molecules For Treating Nervous System Injuries

ITF
2021

Therapeutics Potential of Low Frequency Stimulation at Pons Nuclei (PN) in Acute and Chronic Model of Epilepsy in Mice

HMRF
2021

TNF-α Orchestrates Experience-Dependent Balancing of Excitation-Inhibition in the Olfactory Cortex

GRF
2020

A Novel CCK Receptor Regulates the Long-term Potentiation of Inhibition in the Auditory Cortex

GRF
2020

Calcium Wide-Field Imaging as a Tool for Evaluating Cochlear Implant Stimulation Strategies in the Auditory Cortex

HMRF
2020

Chronic Pain Induces Hypomyelination: A Causal Mechanism for Brain Circuitry Desynchronization and Impaired Decision Making.

GRF
2020

Development of Antagonists for Alleviating Epilepsy

ITF-InnoHK
2020

Development of CCK Agonists as a Stratagem for Curing Tinnitus

ITF-InnoHK
2020

FSH Antibody Design and Production

ITF-InnoHK
2020

FSH Antibody Screen and Selection for Biology and Pharmacology Studies in Animal Models of Diseases

ITF-InnoHK
2020

FSH Lead Antibodies Identification and Selection for Process Development

ITF-InnoHK
2020

Generation of Spinal Dorsal GABAergic Neurons from Human Urine Cells by Defined Transcriptional Factors for the Treatment of Neuropathic Pain in Spinal Cord Injury

GRF
2020

Hearing Loss-induced Tinnitus Alleviation by Cortical Map Reorganization

GRF
2020

Hunger-dependent Control of Olfactory Cortical Circuits Regulates Food-seeking Behavior

GRF
2020

In-Vitro and In-Vivo Assay Platforms for Assessing Drug Efficacy for Brain Disorders

ITF-InnoHK
2020

Large-scale Neural Oscillations Play a Primary Role in Fundamental Cognitive Functions

ITF-InnoHK
2020

Mechanism-Based Studies on the Role of CCKBR in Brain Health

ITF-InnoHK
2020

Preserving the Brain Extracellular Matrix Using Small Molecule Drugs as a Strategy for Blocking Neural Degeneration

ITF-InnoHK
2020

Sensitivity to Envelope and Pulse Timing Interaural Time Differences in Prosthetic Hearing

GRF
2020

Small-Molecule Based Therapy in Treating Peripheral and Central Nervous System Injuries

HMRF
2020

The Role of the Stress Granule Protein G3BP1 in Regulating Protein Synthesis and Dendritic Spine Maturation in Neuron

GRF
2020

Therapeutic Potential of a Novel Deep Brain Stimulation Target Site And Neural Prosthetic Device For Treating Parkinson’s Disease

ITF
2019

CCK-B Receptor Antagonists For The Treatment Of Depression Especially Chronic Pain Comorbid Depression Of Elderly

ITF
2019

Investigating the Effect of Amyotrophic Lateral Sclerosis (ALS)-Associated FUS Mutations on Connectivity of Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neuron

HMRF
2019

Investigating the Therapeutic Potential of Human Neural Stem Cells by Suppressor of Fused (SUFU) Knockdown in a Spinal Cord Injury Model

HMRF
2019

Is Impaired Binaural Hearing in Cochlear Implantees Caused by Lack of Experience or Inappropriate Stimulation?

GRF
2019

Neuroplasticity Induced by the Administration of Cholecystokinin Tetrapeptide and Noise Exposure as a Novel Strategy for the Treatment of Tinnitus

HMRF
2019

Temporal Weighting Functions for Spatial Cues and Their Potential Relevance for Better Binaural Hearing with Cochlear Implants

HMRF
2019

Unraveling the Therapeutic Potential of a Small Molecule Activator of Mitochondrial Fusion and Mechanistic Role of Mitochondria in Axon Regeneration

GRF
2019

探索源自内嗅皮层的胆囊收缩素对于新皮层跨模态联合学习的关键性调节作用

Project funded by the Mainland Government
2019

源于内嗅皮层的胆囊收缩素对于新皮层癫痫的促发作用

Project funded by the Mainland Government
2018

A Stem Cell Approach to Dissect the Molecular Basis of Neurodegenerative Diseases

TBRS
2018

A Stem Cell Approach to Dissect the Molecular Basis of Neurodegenerative Diseases

TBRS
2018

BrainPredictDynamics (Grant no, 750459)

Contract Research
2018

Cholecystokinin Administration Rescues Thalamocortical Neuroplasticity in Old Rodents

GRF
2018

Cortical Mechanisms of Temporal Predictions in Processing Rhythmic Sounds and Speech

EU-RGC
2018

Impaired Communications in Anterior Cingulate Cortex Neural Network in the Rats with Trigeminal Neuropathic Pain Is Associated with Decision-making Deficits

HMRF
2018

Impairment of Schemas and Memory Consolidation and Disruption of Schemas-linked Interactions between Hippocampal and Anterior Cingulate Cortex in Chronic Visceral Pain

GRF
2018

Inhibitory Gating of Neural Circuits for Dynamic Representation of Distinct Odor Features

ECS
2018

Investigating the Dual Function of the Epilepsy-related Gene tbc1d24 in Regulating Excitatory and Inhibitory Synapses of Neuron

GRF
2018

Neural Mechanisms of Prediction Signalling along the Cortical Auditory Pathway

GRF
2018

Neuroprotection by Driving Microglia M2 Polarization after Traumatic Brain Injury: Therapeutic and Mechanistic Approaches

GRF
2018

The Study of Glioma-derived Exosomes in Tumor Progression via MCT1 and Its Ancillary Protein, CD147

GRF
2018

Therapeutic Potential of Activator Protein 4 in Peripheral Nerve Injury

HMRF
2018

Tinnitus Alleviation by Activation of Dendritic IA Channels

GRF
2017

Assay Platforms for CCK-B Receptor Agonists as Potential Treatment for Amnestic Mild Cognitive Impairment

ITF
2017

Dissecting the Novel Role of Formin-2 in Axonal Regeneration and the Underlying Mechanisms

GRF
2017

GABAergic Cholecystokinin Enhances the Local Inhibitory Effect in the Auditory Cortex

GRF
2017

L-lactate Release by Optogenetic Activation of Astrocytes Rescues Decision-making Deficit in Visceral Hypersensitive Rats

NSFC
2017

Natural Sound Statistics in Auditory Scene Analysis

GRF
2017

Role of Oligodendroglial MCT1 in Myelination of the Neonatal Brain

ECS
2017

TNF-a–Mediated Mechanism and Treatment of Hearing Loss-induced Tinnitus

HMRF
2016

Cortical Cholecystokinin as a Chemical Switch Enabling Auditory Long-term Potentiation in the Thalamus

GRF
2016

The Neurobiological Mechanisms of Schizophrenia via Graphene-based Wearable Electronics

ECS
2014

How Brain Encodes Memory

Donation
2014

Development of Anti-cancer Therapy with Externally Activated Nanomedicine

ITF
2014

How Brain Encodes Memory

Donation

19 October 2022