This course is intended to promote evidence-based approach in veterinary medicine practice and critical appraisal of scientific literature to support clinical activities and decision making. Basic skills in the critical assessment of clinical literature will be taught, including systematic search of scientific literature, the basic principles of study design, and critically assessing and applying information from the literature to answer clinical questions. Students will practice the theoretical concepts by conducting critical appraisal of journal articles, as well as answering a PICO (Patient/problem, Intervention/exposure, Comparison/control, Outcome) question using a systematic review strategy and preparing a knowledge summary. By the end of the course, students will be able to critically appraise scientific literature, and apply an evidence-based approach in answering clinical questions.