Understanding the molecular and cellular mechanisms of neuronal function is not only crucial for gaining fundamental insights into how the brain works, but is also pivotal to identify new therapeutic targets for various brain disorders.  This course aims to (1) equip students with the basic knowledge of molecular events, signal transduction pathways and cellular specializations within the brain; (2) introduce some of the latest frontiers on understanding how neurons function at the molecular and cellular levels; and (3) describe the latest technologies and tools in studying neuronal function.  This interdisciplinary course provides detailed explanation on the molecular and cellular basis of various neuronal processes, with focus on intracellular transport, formation and plasticity of synapses, as well as molecular and cellular aberrations during neurodegeneration and neurodevelopmental disorders.  Through wide range of teaching activities including tutorial discussions, paper presentations and essay writing, we aim to inspire students on the different fascinating aspects of molecular and cellular neuroscience.