- 1B-110, 1/F, Block 1, To Yuen Building
- +852 3442-9187
- +852 3442-0549
- li.wang@cityu.edu.hk
- CityU Scholars
- Lab Website
- Metabolism • Cardiovascular • Drug screen • Secretory proteins • Organ crosstalk
Academic Qualifications
- PhD in Biomedical Sciences, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China, 2011-2014
- MSc in Biochemistry and Molecular Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences (CAS), China, 2003-2006
- BSc in Biology, National Base of Biology Education, Yunnan University, China, 1998-2002
Previous Academic Positions Held
- Research Associate
School of Biomedical Sciences, The Chinese University of Hong Kong, 07/2019–09/2021 - Postdoctoral Fellow
School of Biomedical Sciences, The Chinese University of Hong Kong, 07/2014–06/2019 - Research Assistant
Department of Biology and Chemistry, City University of Hong Kong, 2010–2011 - Research Assistant
Department of Physiology, The University of Hong Kong, 10/2008–10/2009 - Research Assistant
Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 07/2006–10/2008
Present Academic Position
Assistant Professor, Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China (September 2021 –)
Research Interests
- Hemodynamic shear stress and the endothelium in the process of atherosclerosis
- The role of Hippo pathway in cardiovascular regulation
- The endocrine function of endothelium in health and disease
- Identification of new biomarker(s) for early diagnosis of atherosclerotic vascular disease
- Identification of new compounds for atherosclerosis prevention and treatment
- Inter-organ crosstalk and physical exercise
Awards and Patent
- 2019 Higher Education Outstanding Scientific Research Output Award (First-class award), The Ministry of Education, People Republic of China.
- Research Excellence Award 2017 based on my publication in Nature in December 2016 from the Chinese University of Hong Kong
- Huang Yu, Wang Li. US Provisional Application No. 62/431,094 filed on 7 December 2016.
Selected publications
- Wang L, Luo JY, Li B, Tian XY, Chen LJ, Huang Y, Liu J, Deng D, Lau CW, Wan S, Ai D, Mak KL, Tong KK, Kwan KM, Wang N, Chiu JJ, Zhu Y & Huang Y (2016) Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. Nature 540:579-581. Commented in Nature News and Views, Nature 540:531-532.
- Zhang H, Liu J, Qu D, Wang L, Wong CM, Lau CW, Huang Y, Wang YF, Huang H, Xia Y, Xiang L, Cai Z, Liu P, Wei Y, Yao X, Ma RCW & *Huang Y (2018) Serum exosomes mediate delivery of arginase 1 as a novel mechanism for endothelial dysfunction in diabetes. Proceedings of the Academy of National Sciences USA 115(29):E6927-E6936.
- Xu C, Wang L, Zhang Y, Li W, Li J, Wang Y, Meng C, Qin J, Zheng ZH, Lan HY, Mak KKL, Huang Y & Xia Y (2020) Tubule-specific Mst1/2 deficiency induces chronic kidney disease via YAP and non-YAP mechanisms. Journal of The American Society of Nephrology 31(5):946-961 with editorial (Journal of the American Society of Nephrology 31(5):893-894).
- Qu D, Wang L, Huo M, Song W, Lau CW, Xu J, Xu A, Yao X, Chiu JJ, Tian XY & Huang Y (2020) Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation. Cardiovascular Research 116(1):226-236.
- Jiang MC, Ding HY, Huang Y, Wang L (2021) Shear Stress and Metabolic Disorders-Two Sides of the Same Plaque. Antioxidants & Redox Signaling. ahead of print http://doi.org/10.1089/ars.2021.0126.
20 October 2021