The demand for precise measurement and instrumentation are increasing day by day for modern industries. This course will provide a coherent and comprehensive introduction to the fundamental concepts, design, fabrication methods underpinning the measurement and instrumentation systems, in the context with applications in various engineering settings. Various approaches to model, analyse, and optimize the measurement and instrumentation systems will also be covered. The state of the art in the integration and assembling of the measurement and instrument systems will be discussed.